2026-10-08 マックス・プランク研究所
A photoreactor capable of producing atomic hydrogen. © MPIKG
＜関連情報＞
- https://www.mpg.de/27021418/atomic-hydrogen-from-the-photoreactor
- https://pubs.acs.org/jacsat/article/148/35/37576/5328961/A-Synthetic-Method-to-Hydrogen-Radicals
水素ラジカルの合成法 A Synthetic Method to Hydrogen Radicals
Nils J. Flodén;Alberto Collauto;Peter H. Seeberger;Roopender Kumar
Journal of the American Chemical Society Published:August 25, 2026
DOI:https://doi.org/10.1021/jacs.6c07870
Abstract
Atomic hydrogen (H•), the union of an electron and a proton, is the smallest radical of the universe. Over the past century, advanced techniques such as electric discharge and mercury UV sensitization enabled a fundamental understanding of the reactivity of H• but fell short of providing synthetic methods to exploit its intriguing properties. Here we report a light-mediated method to access hydrogen radicals under synthetically useful conditions. This strategy enabled the mild, metal-free reduction of highly functionalized alkenes and halides. Mechanistic, EPR, and DFT studies suggest hydrogen radical generation via a Rydberg radical intermediate, with potential applications across the chemical and biological sciences.
