ダイヤモンド量子センサで微弱磁場計測を短距離・高感度化ー脳磁場計測に向けた低発熱ラムゼー磁力計を開発ー

2026-07-23 東京科学大学

東京科学大学、物質・材料研究機構(NIMS)、量子科学技術研究開発機構(QST)、デンソーなどの研究グループは、ダイヤモンド中の窒素-空孔中心(NVセンタ)を利用した高感度量子磁気センサを開発し、室温・低発熱で生体近傍の微弱磁場を高精度に計測できる技術を実証した。光閉じ込めダイヤモンド導波路と小型基板型マイクロ波アンテナを組み合わせることで、レーザー出力を210 mWまで低減しながら、センサと試料間距離を2.0 mmに短縮し、100~400 Hz帯で2.93 pT/√Hzの磁場感度を達成した。また、動作時の温度上昇を約13℃に抑え、生体安全性を確保するとともに、脳磁場を模擬したドライファントムでは77.7 pTの微弱磁場を平均化なしで検出することに成功した。本成果は、従来の超伝導量子干渉素子(SQUID)に比べて小型・低コスト・室温動作という利点を備え、将来的なウェアラブル脳磁計(MEG)や心磁計(MCG)、神経科学・医療診断・創薬分野への応用が期待される。

ダイヤモンド量子センサで微弱磁場計測を短距離・高感度化ー脳磁場計測に向けた低発熱ラムゼー磁力計を開発ー
図1. (a)磁石アレイを含むダイヤモンド量子センサ全体図。(b)センサヘッドの拡大図。

<関連情報>

ラムゼイ干渉法を用いた高感度ダイヤモンドNV磁力計(センサーとサンプル間の距離が短い) A highly sensitive diamond NV magnetometer using Ramsey interferometry with a short sensor-to-sample distance

Yuta Araki;Takeharu Sekiguchi;Yuji Hatano;Naota Sekiguchi;Chikara Shinei;Masashi Miyakawa;Takashi Taniguchi;Tokuyuki Teraji;Hiroshi Abe;Shinobu Onoda;Takeshi Ohshima;Takayuki Shibata;Mutsuko Hatano;Takayuki Iwasaki
Applied Physics Letters  Published:July 22 2026
DOI:https://doi.org/10.1063/5.0334709

In this study, we developed a diamond quantum magnetometer based on Ramsey interferometry with a short sensor-to-sample distance. Conventional biomagnetic sensors with ensemble nitrogen-vacancy centers using continuous-wave optically detected magnetic resonance and Ramsey methods typically rely on watt-level lasers to achieve high sensitivity, resulting in thermal issues. In contrast, by employing the light-trapping diamond waveguide technique in a high-pressure and high-temperature diamond sample treated with electron beam irradiation, we obtained a high optical power conversion efficiency of 9.5%, enabling us to simultaneously achieve a high sensitivity of 2.93(7)  in the 100–400 Hz frequency range and a minimal temperature increase of only approximately 13 K at a low laser power of 210 mW. Using a dry phantom designed to mimic magnetoencephalography signals, we measured a weak magnetic field of 77.7(2) pT without signal averaging at a sensor-to-sample distance of 2.5 mm. This short distance measurement prevents severe spatial signal attenuation, yielding a high signal-to-noise ratio. The development here is crucial for practical biomagnetic applications based on Ramsey interferometry.


高感度磁力計は、センサーとサンプル間の距離を縮めることで生体磁気センシングを向上させる Highly sensitive magnetometer boosts biomagnetic sensing by closing sensor-to-sample distance

Adam Liebendorfer
Scilight  Published:July 22 2026
DOI:https://doi.org/10.1063/10.0044530

Detecting biomagnetic fields, such as in magnetoencephalography — a technique for understanding pathologies such as seizures — has remained a challenge for researchers due to steep signal decays with distance. Diamond quantum sensors are uniquely suited to minimize this sensor-to-sample distance.

Araki et al. developed a highly sensitive Ramsey-based ensemble magnetometer for biomagnetic field sensing. Utilizing a printed-circuit-board microwave antenna, the group’s device shortens the sensor-to-sample distance to 2 millimeters, achieving an effective detection capability directly from the source previously unattainable by conventional high-power approaches.

The device marks a departure from conventional sensors, where high-power laser-based approaches create thermal issues in samples.

“The true innovation of our work lies in a conceptual shift: moving away from simply chasing absolute sensitivity, which typically requires high thermal loads, to optimizing the effective signal-to-noise ratio in a practical, close-proximity geometry,” said author Takayuki Iwasaki. “By demonstrating how to overcome the thermal barriers of pulsed protocols, we hope this paper paves the way for a broader transition in the field from conventional continuous-wave optically detected magnetic resonance methods to more advanced, Ramsey-based biomagnetic sensors.”

Comparable Ramsey applications have achieved a 6.5-millimeter sensor-to-sample distance.

The device employed a waveguide technique that trapped light in high-pressure, high-temperature diamond samples treated with electron beam radiation, housing nitrogen-vacancy centers, which boosted the device’s photon conversion efficiency to 9.5%

The new magnetometer detects magnetic fields as weak as 77.7 picoteslas, maintaining a minimal temperature increase of 13 K and an average sensor-to-sample distance of 2.5 millimeters, boosting the signal-to-noise ratio.

To maintain a high sensitivity during extended biomagnetic field measurements, the group next plans to implement active microwave feedback that dynamically tracks and cancels ambient temperature drift.

Source: “A highly sensitive diamond NV magnetometer using Ramsey interferometry with a short sensor-to-sample distance,” by Yuta Araki, Takeharu Sekiguchi, Yuji Hatano, Naota Sekiguchi, Chikara Shinei, Masashi Miyakawa, Takashi Taniguchi, Tokuyuki Teraji, Hiroshi Abe, Shinobu Onoda, Takeshi Ohshima, Takayuki Shibata, Mutsuko Hatano, and Takayuki Iwasaki, Applied Physics Letters (2026). The article can be accessed at https://doi.org/10.1063/5.0334709.

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