2023-10-23 ワシントン大学セントルイス校
◆この微小プローブは、微小な球形の空間に光を閉じ込める能力を持つ「ウィスパリングギャラリーモード」を活用し、さまざまな分野で応用されることが期待されています。この新しいデバイスは、微小センサーの世界で新たな解決策を提供し、感度向上と検出領域の拡大を実現しました。
◆この技術は、生体医療モニタリング、化学イメージング、磁気センシング、振動検出など、さまざまな分野での応用に影響を与える可能性があります。
＜関連情報＞
- https://engineering.wustl.edu/news/2023/Ultrahigh-sensitivity-microprobe-optimizes-detection-of-molecular-fingerprints.html
- https://www.nature.com/articles/s41377-023-01276-2
ラマン分光とイメージングのためのウィスパリングギャラリーモードマイクロプローブ A whispering-gallery scanning microprobe for Raman spectroscopy and imaging
Wenbo Mao,Yihang Li,Xuefeng Jiang,Zhiwen Liu & Lan Yang
Light: Science & Applications Published:05 October 2023
DOI:https://doi.org/10.1038/s41377-023-01276-2
Abstract
Optical whispering-gallery-mode microsensors are a promising platform for many applications, such as biomedical monitoring, magnetic sensing, and vibration detection. However, like many other micro/nanosensors, they cannot simultaneously have two critical properties – ultrahigh sensitivity and large detection area, which are desired for most sensing applications. Here, we report a novel scanning whispering-gallery-mode microprobe optimized for both features and demonstrate enhanced Raman spectroscopy, providing high-specificity information on molecular fingerprints that are important for numerous sensing applications. Combining the superiorities of whispering-gallery modes and nanoplasmonics, the microprobe exhibits a two-orders-of-magnitude sensitivity improvement over traditional plasmonics-only enhancement; this leads to molecular detection demonstrated with stronger target signals but less optical power required than surface-enhanced-Raman-spectroscopy substrates. Furthermore, the scanning microprobe greatly expands the effective detection area and realizes two-dimensional micron-resolution Raman imaging of molecular distribution. The versatile and ultrasensitive scanning microprobe configuration will thus benefit material characterization, chemical imaging, and quantum-enhanced sensing.
