研究者ら農業用に適した有機ナノザイムを開発(U of I researchers develop organic nanozymes suitable for agricultural use)

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2023-10-16 イリノイ大学

◆イリノイ大学の研究者たちは、生物医学と化学工学での応用を目指し、自然の酵素の特性を模倣した合成材料であるナノ酵素を開発しました。通常のナノ酵素は有害で高価であるため、農業や食品科学には不向きでしたが、彼らは有機で非有害かつコスト効果的なOCナノ酵素を開発し、グリホサートなどの農薬の検出に活用することを目指しています。このナノ酵素は環境にもやさしく、農産物の安全性を向上させるテストキットの開発が期待されています。

<関連情報>

農業用除草剤検出のための有機化合物ベースのナノザイム Organic compound-based nanozymes for agricultural herbicide detection

Dong Hoon Lee  and  Mohammed Kamruzzaman
Nanoscale  Published:28 Jul 2023
DOi:https://doi.org/10.1039/D3NR02025H

Abstract

Nanozymes are increasingly being used for agricultural applications, but their adoption is limited as they are generally considered toxic, have low cost-effectiveness, and pose complexity of fabrication. In this study, an organic compound-based, peroxidase-like nanozyme (OC nanozyme) was developed for use in the agricultural environment. This nanozyme was synthesized through a self-assembled one-pot particle synthesis process, interacting with urea and the metal ion to form a homogenous nanoparticle containing partially mimicked cofactors (Fe–N) of the natural enzyme. The OC nanozyme exhibited decent kinetic properties (H2O2/Km:0.056 mM and Vmax:2.19 μM s−1) and pH stability. The OC nanozyme was successfully used to detect glyphosate via integrated colorimetric assay, with a good limit of detection (LOD) of at least 0.001 ng mL−1. The authors envision that this agricultural-friendly OC nanozyme holds great potential for a wide range of agricultural applications.

研究者ら農業用に適した有機ナノザイムを開発(U of I researchers develop organic nanozymes suitable for agricultural use)

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