指紋を10秒で検出する生体適合性蛍光スプレーを開発(Scientists develop biocompatible fluorescent spray that detects fingerprints in ten seconds)

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2024-02-26 バース大学

水溶性で無毒な蛍光スプレーが開発され、わずか数秒で指紋を可視化可能。従来の方法よりも安全で迅速であり、DNA証拠を傷つけない。青色光下で発光し、指紋の色に合わせて2つの色の染料を提供。微粒子スプレーは飛沫を防ぎ、レンガなどの表面でも素早く作用。中国の上海師範大学と英国のバース大学の科学者が開発し、現在、企業との協力で販売を進めている。

<関連情報>

緑色蛍光タンパク質発色団を利用したポータブルシステムによる潜在指紋取得プローブ De Novo Green Fluorescent Protein Chromophore-Based Probes for Capturing Latent Fingerprints Using a Portable System

Nanan Ruan, Qianfang Qiu, Xiaoqin Wei, Jiajia Liu, Luling Wu, Nengqin Jia, Chusen Huang, and Tony D. James
Journal of the American Chemical Society  Published:January 8, 2024
DOI:https://doi.org/10.1021/jacs.3c11277

Abstract

指紋を10秒で検出する生体適合性蛍光スプレーを開発(Scientists develop biocompatible fluorescent spray that detects fingerprints in ten seconds)

Rapid visualization of latent fingerprints, preferably at their point of origin, is essential for effective crime scene evaluation. Here, we present a new class of green fluorescent protein chromophore-based fluorescent dyes (LFP-Yellow and LFP-Red) that can be used for real-time visualization of LFPs within 10 s. Compared with traditional chemical reagents for LFPs, these fluorescent dyes are completely water-soluble, exhibit low cytotoxicity, and are harmless to users. Level 1–3 details of the LFPs could be clearly revealed through “off–on” fluorescence signal readout. Additionally, the fluorescent dyes were constructed based on an imidazolinone core and so do not contain pyridine groups or metal ions, which ensures that the DNA is not contaminated during extraction and identification after the LFPs are treated with the dyes. Combined with our as-developed portable system for capturing LFPs, LFP-Yellow and LFP-Red enabled the rapid capture of LFPs. Therefore, these green fluorescent protein chromophore-based probes provide an approach for the rapid identification of individuals who were present at a crime scene.

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