2023-12-07 ペンシルベニア州立大学(PennState)
◆この新たな形状と制御手法により、微小なプロペラを操り、重合体カーゴ粒子を捕獲・輸送する可能性が開かれ、医薬品デリバリーやラボ・オン・ア・チップ技術の進展に寄与する見通し。
＜関連情報＞
- https://www.psu.edu/news/engineering/story/spinning-control-propeller-shape-helps-direct-nanoparticles-researchers-say/
- https://onlinelibrary.wiley.com/doi/10.1002/smll.202304773
多機能キラル化学動力マイクロプロペラによる荷物の輸送と操作 Multifunctional Chiral Chemically-Powered Micropropellers for Cargo Transport and Manipulation
Ashlee D. McGovern, Mu-Jie Huang, Jiyuan Wang, Raymond Kapral, Igor S. Aranson
Small Published: 07 November 2023
DOI:https://doi.org/10.1002/smll.202304773
Abstract
Practical applications of synthetic self-propelled nano and microparticles for microrobotics, targeted drug delivery, and manipulation at the nanoscale are rapidly expanding. However, fabrication limitations often hinder progress, resulting in relatively simple shapes and limited functionality. Here, taking advantage of 3D nanoscale printing, chiral micropropellers powered by the hydrogen peroxide reduction reaction are fabricated. Due to their chirality, the propellers exhibit multifunctional behavior controlled by an applied magnetic field: spinning in place (loitering), directed migration in the prescribed direction, capture, and transport of polymer cargo particles. Design parameters of the propellers are optimized by computation modeling based on mesoscale molecular dynamics. It is predicted by computer simulations, and confirmed experimentally, that clockwise rotating propellers attract each other and counterclockwise repel. These results shed light on how chirality and shape optimization enhance the functionality of synthetic autonomous micromachines.
