2026-08-13 理化学研究所
図1 長期低温処理による茎葉および根の再生能力の向上
＜関連情報＞
- https://www.riken.jp/press/2026/20260813_1/index.html
- https://www.cell.com/developmental-cell/abstract/S1534-5807(26)00278-9
長時間の低温曝露はシロイヌナズナの再生能力を高める Prolonged cold exposure enhances regeneration potential in Arabidopsis
Fu-Yu Hung ∙ Yetkin Caka Ince ∙ Ayako Kawamura ∙ … ∙ Miguel Moreno-Risueno ∙ Keqiang Wu ∙ Keiko Sugimoto
Developmental Cell Published: August 12, 2026
DOI:https://doi.org/10.1016/j.devcel.2026.07.009
Highlights
- The winter-like prolonged cold primes regeneration potential in Arabidopsis
- CBFs-HAG1-mediated H3 acetylation promotes regeneration after prolonged cold exposure
- WOX5 is one of the key downstream effectors in prolonged cold-promoted regeneration
Summary
Prolonged cold exposure over winter impacts plant growth and development, but its role beyond flowering regulation remains underexplored. In this study, we show that extended cold enhances regenerative capacity, promoting both callus formation and shoot regeneration in Arabidopsis. This enhancement is mediated by the cold-induced AP2/ERF transcription factors C-REPEAT/DRE-BINDING FACTOR 1 (CBF1), CBF2, and CBF3, which interact with the histone acetyltransferase (HAT) HISTONE ACETYLTRANSFERASE OF THE GNAT FAMILY 1 (HAG1). The CBFs recruit HAG1 to the loci of key regeneration regulators, such as WUSCHEL-RELATED HOMEOBOX 5 (WOX5), to promote their expression via histone acetylation. Our findings thus uncover an epigenetic mechanism by which prolonged cold primes plants for enhanced regeneration, highlighting how environmental cues influence developmental plasticity in plants.
