2026-03-14 中国科学院（CAS）
Schematic illustration of the Eu-MOF design strategy and the mechanism for TATP detection. (Image by XTIPC)
＜関連情報＞
- https://english.cas.cn/newsroom/research-news/202603/t20260316_1152711.shtml
- https://onlinelibrary.wiley.com/doi/10.1002/agt2.70294
Eu-MOFにおける分子内水素結合切断を介したpgレベルのTATPのワンステップ、特異的、かつ蛍光センシング One-Step, Specific, and Fluorescent Sensing of pg-Level TATP via Intramolecular Hydrogen Bond Breaking in Eu-MOFs
Xu Cheng, Zhenzhen Cai, Jiahao Dong, Jiawen Li, Chuanfang Zhao, Jinlong Ma, Qingchun Zhou, Xincun Dou
Aggregate Published: 11 February 2026
DOI:https://doi.org/10.1002/agt2.70294
ABSTRACT
The design of zero-background fluorescent sensing materials with specific functionalities is of great significance. Here, a special Eu-MOF with nonfluorescent emission was designed and driven by H2O-induced cascade reaction through modulating the number of hydroxyl groups in ligands to enhance the signal-to-noise ratio, sensitivity, and reaction speed toward triacetone triperoxide (TATP). It is found that only when the ligand was selected as 2,5-dihydroxyterephthalic acid (DHTA), and with the introduction of H2O, the intramolecular hydrogen bond could be changed to a weaker intermolecular hydrogen bond, which would be interrupted and oxidized from the original enol structure to ketone, producing the fluorescence turn-on response toward TATP. The special Eu-MOF exhibited a high-performance sensing for TATP, with fast response (<1 s), low limit of detection (LOD, 36.1 nM), superior selectivity even in the presence of 28 kinds of interferents, including the very similar hydrogen peroxide, strong robustness, and a practical detecting ability of 5 pg airborne TATP particle. Furthermore, we validated the practical feasibility of the specific Eu-MOF by integrating a sensing chip into a portable detector, thereby confirming that this MOF exhibits considerable potential for trace-level TATP detection in real-world application scenarios. The present nonfluorescent MOF design strategy and the elaborate modulation of the conformation in MOF structure would provide a new pathway for the exploration of novel functional MOFs as well as high-performance sensing methodologies.
