2026-02-18 東京大学
図1. 化学反応を駆動力に自動開閉するナノポア。
＜関連情報＞
- https://www.t.u-tokyo.ac.jp/press/pr2026-02-18-001
- https://www.nature.com/articles/s41467-026-68800-x
化学駆動型自律ナノポア膜 Chemistry-driven autonomous nanopore membranes
Makusu Tsutsui,Wei-Lun Hsu,Denis Garoli,Ali Douaki,Yuki Komoto,Hirofumi Daiguji & Tomoji Kawai
Nature Communications Published:18 February 2026
DOI:https://doi.org/10.1038/s41467-026-68800-x
Abstract
Fabrication of pores at the atomic scale remains a significant challenge in modern nanotechnology, hindering the study of ion transport and molecular dynamics in confined spaces. Here, we introduce a chemically controllable break-membrane approach that enables the repeated formation and closure of nanoscale pores in SiNx membranes through manipulating the in-pore electrochemical reaction conditions by transmembrane voltage. Ionic current measurements reveal distinct conductance features that are consistent with ion dehydration and transport through highly confined channels approaching sub-nanometer dimensions. The scalable nature of this platform, which allows multiple pores to be actuated simultaneously, offers a powerful tool for probing ion transport and fluid dynamics in extreme confinement. Beyond advancing fundamental understanding of ion transport and fluid dynamics, this chemically driven membrane system holds promise for applications in single-molecule sensing, neuromorphic computing, and nanoreactor design.
