2025-11-06 九州大学
図1・シロイヌナズナにおける窒素環境の変化に対する根の生長の変化の模式図
<関連情報>
- https://www.kyushu-u.ac.jp/ja/researches/view/1356
- https://www.kyushu-u.ac.jp/f/63847/25_1106_01.pdf
- https://www.cell.com/current-biology/abstract/S0960-9822(25)01260-6
アラビドプシスLOHN1ペプチドは全身窒素飽和シグナル伝達の制御下で側根間隔を調節する Arabidopsis LOHN1 peptide modulates lateral root spacing under the control of systemic nitrogen-satiety signaling
Kazuhiro Ito ∙ Tomoya Sonoda ∙ Yuki Hisanaga ∙ … ∙ Kousuke Hanada ∙ Koh Iba ∙ Kensuke Kusumi
Current Biology Published:October 24, 2025
DOI:https://doi.org/10.1016/j.cub.2025.09.060
Highlights
- Arabidopsis secretory peptide LOHN1 suppresses LR development under high N supply
- LOHN1 is induced in phloem companion cells at the root tip by shoot-derived glutamate
- N-induced LOHN1 peptide modulates LR priming via regulating auxin transport
- Novel molecular mechanism links N supply to root development in plants
Summary
In Arabidopsis thaliana, high nitrogen (N) levels are known to induce a systemic signal that represses lateral root (LR) development. However, the molecular mechanisms underlying this response remain poorly understood. In this study, we identified a cysteine-rich secretory peptide, LATERAL ROOT OVERPRODUCTION UNDER HIGH-NITROGEN CONDITIONS 1 (LOHN1), as a key signaling molecule involved in translating an N-sufficient nutritional status into a morphological response that inhibits LR development. High N supply induces LOHN1 expression in phloem companion cells at the root tip region under the control of shoot-derived glutamate and glutamate receptor-like channel (GLR). LOHN1 secretion into the apoplastic space regulates the expression of auxin transporter genes to reduce the frequency of LR priming and LR founder cell formation, thereby suppressing LR branching. Our data provide a molecular basis for how plants respond to high N supply and control root architecture to achieve proper plant growth.
