2025-11-27 東京大学,茨城大学,科学技術振興機構
図１：単純な透過X線で区別できなかった物質の区別が可能に
（a）今回開発した透過X線明滅（Transmitted X-ray Blinking：TXB）装置。（b）上段がX線透過像、下段が機械学習による動態像で、上段では区別が難しい明確なミクロ分子動態の区別が可能になった。
＜関連情報＞
- https://www.k.u-tokyo.ac.jp/information/category/press/0028524.html
- https://www.k.u-tokyo.ac.jp/assets/files/ナノ秒X線動画でミクロ分子動態計測に成功_WEB.pdf
- https://opg.optica.org/oe/fulltext.cfm?uri=oe-33-24-51657
透過X線ブリンキングによるポリマー樹脂のサブマイクロ秒分子運動解析 Sub-microsecond molecular motion analysis of polymer resins via transmitted X-ray blinking
Masahiro Kuramochi, Kentaro Hoshisashi, Shunya Shimomura, Daisuke Sasaki, Tatsuya Arai, Kazuhiro Mio, Hiroshi Sekiguchi, Kentaro Uesugi, Yoshio Suzuki, Shotaro Akaho, and Yuji C. Sasaki
Optica Published: November 26, 2025
DOI:https://doi.org/10.1364/OE.573497
Abstract
We developed transmitted X-ray blinking (TXB), a time-resolved transmission imaging technique with 900-nanosecond resolution for probing sub-microsecond molecular dynamics. TXB was applied to semi-crystalline polyetheretherketone (PEEK) and amorphous polyetherimide (PEI), two polymer resins with nearly identical X-ray absorption properties and indistinguishable static transmission images. Single-pixel autocorrelation analysis (spACF) of the TXB data revealed statistically significant differences in dynamic behavior between the two materials, consistent with results from diffracted X-ray blinking (DXB). Although conventional two-dimensional decay constant maps provided limited visual separation, further analysis using machine learning enabled clearer dynamic contrast and >90% classification accuracy. Spectral decomposition also identified periodic fluctuations in the 300–400 kHz range. These results demonstrate that TXB enables material differentiation based on intrinsic dynamic properties, even in the absence of static contrast, and offers new avenues for visualizing subtle motions in soft and biological systems.
