α線がん治療薬の”有効性”を迅速に見える化～α;線放出核種の化学形・放射能同時分析システムを販売開始～

2025-04-18 日本原子力研究開発機構,量子科学技術研究開発機構,明昌機工株式会社

＜関連情報＞

• https://www.jaea.go.jp/02/press2025/p25041802/
• https://link.springer.com/article/10.1007/s10967-020-07353-9

αシンチレーションカメラシステムと薄層クロマトグラフィーを用いた211Atの分析法Analytical method for the determination of 211At using an α-scintillation camera system and thin-layer chromatography

Mariko Segawa,Ichiro Nishinaka,Yosuke Toh & Makoto Maeda
Journal of Radioanalytical and Nuclear Chemistry  Published:28 August 2020
DOI:https://doi.org/10.1007/s10967-020-07353-9

Abstract

²¹¹At is artificially produced for medical purposes. To prevent severe loss of short-lived ²¹¹At, a rapid method analyzing both the radioactivity and all chemical forms was required for related fundamental researches. We propose a new method by means of an α-scintillation-camera system comprising of thin-layer chromatography and a high-sensitive CCD camera. The performance of the system was experimentally verified: low-radioactivity ²¹¹At of 56–672 Bq was measured in a short-time of 1000 s and all chemical forms of ²¹¹At were evaluated. The results reveal that the method enables us to analyze two features of ²¹¹At with significantly short-time.