抗生物質や化学物質を使わずに細菌を殺すことができる改良ステンレス鋼(This Modified Stainless Steel Could Kill Bacteria Without Antibiotics or Chemicals)

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2024-05-20 ジョージア工科大学

ジョージア工科大学で開発された電気化学プロセスが、抗生物質耐性を助長することなく細菌感染から守る新しい方法を提供します。この技術は銅の自然な抗菌特性を利用し、ステンレス鋼の表面にナノサイズの針状構造を作り、E. coliや黄色ブドウ球菌などの有害な細菌を殺します。安価で便利なこの方法は、病院やキッチンなどの表面汚染を防ぎ、抗生物質の使用を減らす可能性があります。研究では、このプロセスが表面に銅イオンを堆積させ、97%のグラム陰性菌と99%のグラム陽性菌を削減することが示されました。この技術は医療用具やドアハンドル、食品サービスにも応用可能です。

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銅被覆ナノテクスチャー・ステンレス鋼の二重抗菌特性 Dual Antibacterial Properties of Copper-Coated Nanotextured Stainless Steel

Anuja Tripathi, Jaeyoung Park, Thomas Pho, Julie A. Champion
Small  Published: 20 May 2024
DOI:https://doi.org/10.1002/smll.202311546

抗生物質や化学物質を使わずに細菌を殺すことができる改良ステンレス鋼(This Modified Stainless Steel Could Kill Bacteria Without Antibiotics or Chemicals)

Abstract

Bacterial adhesion to stainless steel, an alloy commonly used in shared settings, numerous medical devices, and food and beverage sectors, can give rise to serious infections, ultimately leading to morbidity, mortality, and significant healthcare expenses. In this study, Cu-coated nanotextured stainless steel (nSS) fabrication have been demonstrated using electrochemical technique and its potential as an antibiotic-free biocidal surface against Gram-positive and negative bacteria. As nanotexture and Cu combine for dual methods of killing, this material should not contribute to drug-resistant bacteria as antibiotic use does. This approach involves applying a Cu coating on nanotextured stainless steel, resulting in an antibacterial activity within 30 min. Comprehensive characterization of the surface revealing that the Cu coating consists of metallic Cu and oxidized states (Cu2+ and Cu+), has been performed by this study. Cu-coated nSS induces a remarkable reduction of 97% in Gram-negative Escherichia coli and 99% Gram-positive Staphylococcus epidermidis bacteria. This material has potential to be used to create effective, scalable, and sustainable solutions to prevent bacterial infections caused by surface contamination without contributing to antibiotic resistance.

0501セラミックス及び無機化学製品
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