液体中でも高感度な新型センサー技術(Novel sensing technology 20 times more responsive)

2026-03-17 ペンシルベニア州立大学(Penn State)

ペンシルベニア州立大学(Penn State)の研究チームは、従来比で最大20倍の感度を持つ新しいセンシング技術を開発した。固体だけでなく液体環境でも高い応答性を維持できる点が特徴で、ナノスケールでの表面構造と物理特性を精密に制御することで、微小な変化を高精度に検出可能にした。これにより、生体分子検出や環境モニタリング、医療診断など幅広い応用が期待される。従来技術では難しかった液中での高感度検出を実現し、センサー技術の性能向上と応用範囲拡大に寄与する成果とされる。

液体中でも高感度な新型センサー技術(Novel sensing technology 20 times more responsive)
The team fit sensors built with their new field-effect transistor design onto integrated circuit boards, like the one pictured here, in order to test sensing accuracy and sensitivity. They found that their approach facilitates sensors that are not only responsive, but highly resistant to the signal drift issues that had faced previous designs. Credit: Jaydyn Isiminger / Penn State. Creative Commons

<関連情報>

低ノイズ、ドリフト安定、および調整可能な化学センシングのためのアクティブデュアルゲートグラフェントランジスタ Active dual-gated graphene transistors for low-noise, drift-stable, and tunable chemical sensing

Vinay Kammarchedu,Heshmat Asgharian,Hossein Chenani & Aida Ebrahimi
npj 2D Materials and Applications  Published:13 February 2026
DOI:https://doi.org/10.1038/s41699-026-00674-5  Unedited version

Abstract

Graphene field-effect transistors (GFETs) are among the most promising platforms for ultrasensitive chemical and biological sensing due to their high carrier mobility, large surface area, and low intrinsic noise. However, conventional single-gate GFETs in liquid environments suffer from severe limitations, including signal drift, charge trapping, and insufficient signal amplification. Here, we introduce a dual-gate GFET architecture that integrates a high-κ hafnium dioxide local back gate with an electrolyte top gate, coupled with real-time feedback biasing. This design enables capacitive signal amplification while simultaneously suppressing gate leakage and low-frequency noise. By systematically evaluating seven distinct operational modes, we identify the Differential Mode Fixed configuration as optimal, achieving up to 20× signal gain, >15× lower drift compared with gate-swept methods, and up to 7× higher signal-to-noise ratio across a diverse range of analytes, including neurotransmitters, volatile organic compounds, environmental contaminants, and proteins. We further demonstrate robust multichannel detection using a PCB-integrated GFET sensor array, underscoring the scalability and practicality of the platform for portable, high-throughput sensing. Together, these advances establish a versatile and stable sensing technology capable of real-time, label-free detection of molecular targets under ambient and physiological conditions, with broad applicability in health monitoring, food safety, agriculture, and environmental screening.

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