世界初となる顕微鏡がナノ粒子の3Dゴースト画像を撮影(First-of-its-kind microscope takes 3D ghost images of nanoparticles)

2025-07-28  ローレンスリバモア国立研究所(LLNL)

ローレンス・リバモア国立研究所(LLNL)の研究者らは、世界初の「3D量子ゴーストイメージング顕微鏡」を開発した。量子もつれ光子を用いて、スキャン不要でナノ粒子の3次元像をマイクロメートル精度で取得できる。試料に照射されない光子からゴースト画像を構築し、照射側の散乱データと同期させることで高解像度の立体画像を生成する。従来法よりも低光照射で生体への負荷が少なく、細胞や微生物の動的観察にも応用が期待されている。

世界初となる顕微鏡がナノ粒子の3Dゴースト画像を撮影(First-of-its-kind microscope takes 3D ghost images of nanoparticles)The 3D quantum ghost imaging microscope setup. A laser and crystal (left) are used to make entangled photons, which are split and sent in two directions. One turns left to hit and scatter off a sample, providing a standard image at a 90-degree angle. The other continues straight and is used to construct a ghost image. (Credit: Eshun et al.)

<関連情報>

3D量子ゴーストイメージング顕微鏡 3D quantum ghost imaging microscope

Audrey Eshun, Dominique Davenport, Brandon Demory, Shervin Kiannejad, Paul Mos, Yang Lin, Tiziana Bond, Michael C. Rushford, Erin E. Nuccio, Ty J. Samo, Peter K. Weber, Claudio Bruschini, Edoardo Charbon, and Ted A. Laurence
Optica  Published: July 15, 2025
DOI:https://doi.org/10.1364/OPTICA.565248

Abstract

Quantum ghost imaging uses quantum-entangled photons to generate a two-dimensional image with only a bucket detector at the sample. Here we expand on this approach to generate a three-dimensional image without scanning. A quantum-entangled light source directly links information between a pair of 2D sensors, one of which captures a standard image from one perspective and a second sensor which captures a ghost image from a perpendicular perspective. By correlating the spatial information from the two detectors for each photon pair, we obtain three dimensions of spatial information (x,y , and z ) for each scattered photon. We demonstrate that this system can study microscopic environments by imaging scattering from metallic nanoparticle clusters. This approach has the potential to greatly reduce the flux of light required to obtain a 3D image of a biological sample and thereby extend the number of images that can be obtained before photodamaging the sample.

1700応用理学一般
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