「永遠の化学物質」が健康に与える影響と数十億ドル規模の経済損失を関連付ける研究(New research links health impacts related to ‘forever chemicals’ to billions in economic losses)

2025-12-08 アリゾナ大学

アリゾナ大学などの研究チームは、PFAS(いわゆる“永遠の化学物質”)曝露がもたらす健康影響と、それに起因する米国の年間経済損失額を初めて詳細に推計した。PFAS は水・食品・製品などを通じて広く蓄積し、がん、肝疾患、糖尿病、甲状腺疾患、妊娠高血圧、低出生体重など多岐にわたる疾患リスクを高めることが知られる。本研究は、最新の疫学データと曝露レベルを統合し、医療費・生産性低下・寿命短縮による経済損失を算定。その結果、PFAS に関連する米国の年間損失は 推定数千億ドル規模 に達し、公衆衛生・経済に深刻な負担を与えていることが判明した。研究者らは、PFAS の規制強化、除去技術の導入、水質基準の更新、企業による排出削減が最も費用対効果の高い対策となり得ると指摘する。今回の結果は、政策決定者が環境汚染対策の費用よりもはるかに大きい「無策による損失」を認識すべきであることを示している。

「永遠の化学物質」が健康に与える影響と数十億ドル規模の経済損失を関連付ける研究(New research links health impacts related to ‘forever chemicals’ to billions in economic losses)

“Forever chemicals” that contaminate drinking water in cities across the U.S. impose annual social costs of at least $8 billion, according to a U of A-led study. The costs encompass medical care, long-term health impacts and reduced lifetime earnings.

<関連情報>

PFASに汚染された飲料水は乳児に害を及ぼす PFAS-contaminated drinking water harms infants

Robert Baluja, Bo Guo, Wesley Howden, +1 , and Derek Lemoine

Proceedings of the National Academy of Sciences  Published:December 8, 2025

DOI:https://doi.org/10.1073/pnas.2509801122

Significance

Per- and polyfluoroalkyl substances (PFAS), so-called “forever chemicals,” are pollutants of increasing concern. However, there is not yet firm evidence that the types of PFAS exposure occurring in daily life cause human health impacts. We show that New Hampshire mothers whose drinking water wells were downstream of PFAS releases had more extremely low-weight births, more extremely preterm births, and higher infant mortality than did mothers whose wells were upstream of PFAS releases. Mothers did not know the locations of their wells and so should be comparable but for their PFAS exposure. Extrapolating to the rest of the United States, PFAS impose billions of dollars of costs on U.S. residents each year by worsening infant health.

Abstract

There is evidence of widespread human exposure to per- and polyfluoroalkyl substances (PFAS) but limited evidence of the human health impacts of this exposure. Using data on New Hampshire births from 2010–2019, we show that mothers receiving water that had flowed beneath a PFAS-contaminated site, as opposed to comparable mothers receiving water that had flowed toward a PFAS-contaminated site, had 191% [95% CI: 83–298%] higher first-year infant mortality (611 [268–955] additional first-year deaths per 100k births); 168% [42–294%] more births before 28 wk of gestational age (466 [116–817] additional such births per 100k births); and 180% [57–302%] more births with weight below 1,000 g (607 [192–1022] additional such births per 100k births). Extrapolating to the contiguous U.S., PFAS contamination imposes annual social costs of approximately $8 billion. These health costs are substantially larger than current outside estimates of the cost of removing PFAS from the public water supply.

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