2024-11-25 デューク大学(Duke)
デューク大学のエンジニアは、リング共振器を用いた新しい音響ピンセット技術を開発しました。この技術は、従来よりも低い電力で高精度な粒子操作を可能にし、生物学的研究や医療診断、治療において、微小粒子の精密かつ非接触の操作を実現します。この成果は、2024年11月14日に『Science Advances』誌にオンラインで発表されました。
＜関連情報＞
- https://pratt.duke.edu/news/ring-resonators-unlock-new-abilities-in-acoustic-tweezers/
- https://www.science.org/doi/10.1126/sciadv.ads2654
リング共振による音響流体ピンセット Acoustofluidic tweezers via ring resonance
Xianchen Xu, Ke Jin, Kaichun Yang, Ruoyu Zhong, Mingyuan Liu, Wesley Collyer, Shivam Jain, Ying Chen, Jianping Xia, […], and Tony Jun Huang
Science Advances Published:13 Nov 2024
DOI:https://doi.org/10.1126/sciadv.ads2654
Abstract
Ring resonator (RR) devices are closed-loop waveguides where waves circulate only at the resonant frequencies. They have been used in sensor technology and optical tweezers, but controlling micron-scale particles with optical RR tweezers is challenging due to insufficient force, short working distances, and photodamage. To overcome these obstacles, an acoustofluidic RR-based tweezing method is developed to manipulate micro-sized particles that can enhance particle trapping through the resonance interaction of acoustic waves with high Q factor (>3000), more than 20 times greater than traditional acoustic transducers. Particles can be precisely manipulated within the RR by adjusting the signal phase, with trapping amplified by enlarging the connected waveguide. Rapid particle mixing is achieved when particles are placed between the waveguide and RR. The signal path is strengthened by strategically positioning the RR in a two-dimensional plane. Acoustofluidic RR tweezers have immense potential for advancing applications in biosensing, mechanobiology, lab-on-a-chip, and cell-cell communication research.
