2024-10-28 デューク大学(Duke)
＜関連情報＞
- https://pratt.duke.edu/news/new-solvent-free-3d-printing-material-could-enable-biodegradable-implants/
- https://onlinelibrary.wiley.com/doi/abs/10.1002/anie.202414016
分解性ポリ（アリルグリシジルエーテルサクシネート）の合成と無溶剤DLP 3Dプリンティング Synthesis and Solvent Free DLP 3D Printing of Degradable Poly(Allyl Glycidyl Ether Succinate)
Maddison I. Segal, Alexander J. Bahnick, Nicola G. Judge, Matthew L. Becker
Angewandte Chemie International Edition Published: 30 August 2024
DOI:https://doi.org/10.1002/anie.202414016
Graphical Abstract
We report the synthesis of poly(allyl glycidyl ether succinate) (PAGES), a low viscosity, degradable polyester by ring opening copolymerization and its use in combination with degradable thiol crosslinkers to afford a solvent free resin yielding 3D printed parts with minimal shrinkage and residual stress.
Abstract
Digital light processing (DLP) printing forms solid constructs from fluidic resins by photochemically crosslinking polymeric resins with reactive functional groups. DLP is used widely due to its efficient, high-resolution printing, but its use and translational potential has been limited in some applications as state-of-the-art resins experience unpredictable and anisotropic part shrinkage due to the use of solvent needed to reduce resin viscosity and layer dependent crosslinking. Herein, poly(allyl glycidyl ether succinate) (PAGES), a low viscosity, degradable polyester, was synthesized by ring opening copolymerization and used in combination with degradable thiol crosslinkers to afford a solvent free resin that can be utilized in DLP printing. Varying resin formulations of PAGES polymer are shown to decrease part shrinkage from 14 % to 0.3 %. Photochemically printed parts fabricated from PAGES possess tensile moduli between 0.43 and 6.18 MPa and degradation profiles are shown to vary between 12 and 40 days under accelerated conditions based on degree of polymerization and crosslink ratio.
